AKOS BRN-0197

AKOS BRN-0197 - Names and Identifiers

Name	2-Bromo-5-pyridylboronic acid pinacol ester
Synonyms	AKOS BRN-0197 RARECHEM AK ML 0446 2-BROMOPYRIDINE-5-BORONIC ACID PINACOLATE 2-Bromopyridine-5-boronicacidpinacolester 2-BROMO-5-PYRIDYLBORONIC ACID PINACOL ESTER 2-Bromo-5-pyridylboronic acid pinacol ester 2-BROMO-5-PYRIDINEBORONIC ACID PINACOL ESTER 2-Bromopyridine-5-boronic acid pinacol ester 2-BROMOPYRIDINE-5-BORONIC ACID PINACOL ESTER 2-Brom-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin 2-BROMO-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE 2-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 2-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-pyridine pyridine, 2-bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
CAS	214360-62-0
InChI	InChI=1/C11H15BBrNO2/c1-10(2)11(3,4)16-12(15-10)8-5-6-9(13)14-7-8/h5-7H,1-4H3

AKOS BRN-0197 - Physico-chemical Properties

Molecular Formula	C11H15BBrNO2
Molar Mass	283.96
Density	1.34±0.1 g/cm3(Predicted)
Boling Point	345.1±27.0 °C(Predicted)
Flash Point	162.5°C
Vapor Presure	0.000126mmHg at 25°C
pKa	0.78±0.12(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.527
MDL	MFCD03412794

AKOS BRN-0197 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36 - Irritating to the eyes
Safety Description	26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Hazard Class	IRRITANT

AKOS BRN-0197 - Introduction

2-Bromo-5-pyridylboronic acid pinacol ester(2-Bromo-5-pyridylboronic acid pinacol ester) is an organic compound with the following properties:

1. Appearance: White crystalline solid.
2. Molecular formula: C12H16BBrNO2.
3. Molecular weight: 284.07g/mol.
4. Melting Point: about 80-82 degrees Celsius.

The main use of this compound is as an important reagent in organic synthesis. It can be used in the synthesis of various organic compounds containing 2-bromo-5-pyridyl. For example, it can be used as a substrate to react with other compounds in a cross-coupling reaction to generate new compounds. In addition, it can also be used in the synthesis of important intermediates in organic synthesis.

The method of preparing 2-Bromo-5-pyridylboronic acid pinacol ester is generally carried out by the following steps:

1. Reacting 2-bromo -5-bromopyridine with pinacol ester to generate 2-bromo -5-pinacol ester;
2. 2-bromo-5-pinacol ester reacts with boric acid to generate 2-bromo-5-pyridyylboronic acid pinacol ester.

When using 2-Bromo-5-pyridylboronic acid pinacol ester, you need to pay attention to the following safety information:

1. This compound has a certain degree of irritation, contact with the eyes, skin and respiratory tract should be avoided.
2. Wear appropriate protective equipment during operation, such as safety glasses, protective gloves and protective clothing.
3. It should be operated in a well-ventilated laboratory environment and avoid inhaling volatile gases.
4. In the storage and disposal process to comply with the relevant safety procedures and regulations.

It is best to operate and process under the guidance of a laboratory or professional.

Last Update：2024-04-10 22:29:15